Prevalence of Osteoporosis and Hypovitaminosis D at Siriraj Metabolic Bone Disease Clinic

Aasis Unnanuntana, pojchong chotiyarnwong


Objective: To identify the prevalence of osteoporosis and hypovitaminosis D among patients at the Siriraj metabolic bone disease (MBD) clinic and to compare initial metabolic laboratory investigation between the patient with and without history of fragility fracture.
Material and methods: The medical records of 761 patients during the 2012 to 2015 study period were retrospectively reviewed. Patient baseline demographic, clinical, bone mineral density (BMD), and laboratory data were collected and analyzed.
Results: From a total of 708 patients that had baseline BMD data, 422 patients (59.6%) were diagnosed with osteoporosis. Of the 685 patients that had baseline serum 25-hydroxyvitamin D (25(OH)D) level data, 391 patients (57.1%) were diagnosed with hypovitaminosis D (defined as 25(OH)D level <30 ng/mL). When evaluated only in patients with fragility fracture, the prevalence of hypovitaminosis D was 57.6%.
Conclusion: A high prevalence of osteoporosis and hypovitaminosis D was found among patients, with almost two-thirds of patients having a history of fragility fracture. As both a prophylactic and a component of treatment, calcium and vitamin D supplementation should be given to this patient population.
Level of Evidence III, Prognostic retrospective study.

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